Case Report Open Access


Voriconazole-Induced Periostitis: A Radiographic Progression

Alyssa Cubbison, Piotr Obara, Terrence Demos.

Abstract
We present a case of incidentally discovered Voriconazole-induced periostitis in a patient with chronic lymphocytic leukemia. Voriconazole was initiated approximately two years prior to the periostitis discovery on a chest CT for acute on chronic respiratory failure. Because of the asymptomatic nature of the periostitis and its slow development, it was not reported on imaging for over two years. The periostitis was followed retrospectively over a two-year span from the patient’s surveillance imaging. Although there are several cases of periostitis from chronic Voriconazole use in the literature, this case is made unique in its asymptomatic presentation, allowing for a visual display of periostitis progression over two years. This case highlights the fact that Voriconazole-induced periostitis can be asymptomatic and should, therefore, be readily recognized and include a comprehensive differential.

Key words: Periostitis, Voriconazole, CT


 
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Pubmed Style

Cubbison A, Obara P, Demos T. Voriconazole-Induced Periostitis: A Radiographic Progression. J Diagn Imaging. 2017; 2(2): 31-34. doi:10.5455/jdi.20170608104413



Web Style

Cubbison A, Obara P, Demos T. Voriconazole-Induced Periostitis: A Radiographic Progression. www.scopemed.org/?mno=241252 [Access: October 20, 2017]. doi:10.5455/jdi.20170608104413



AMA (American Medical Association) Style

Cubbison A, Obara P, Demos T. Voriconazole-Induced Periostitis: A Radiographic Progression. J Diagn Imaging. 2017; 2(2): 31-34. doi:10.5455/jdi.20170608104413



Vancouver/ICMJE Style

Cubbison A, Obara P, Demos T. Voriconazole-Induced Periostitis: A Radiographic Progression. J Diagn Imaging. (2017), [cited October 20, 2017]; 2(2): 31-34. doi:10.5455/jdi.20170608104413



Harvard Style

Cubbison, A., Obara, P. & Demos, T. (2017) Voriconazole-Induced Periostitis: A Radiographic Progression. J Diagn Imaging, 2 (2), 31-34. doi:10.5455/jdi.20170608104413



Turabian Style

Cubbison, Alyssa, Piotr Obara, and Terrence Demos. 2017. Voriconazole-Induced Periostitis: A Radiographic Progression. Journal of Diagnostic Imaging , 2 (2), 31-34. doi:10.5455/jdi.20170608104413



Chicago Style

Cubbison, Alyssa, Piotr Obara, and Terrence Demos. "Voriconazole-Induced Periostitis: A Radiographic Progression." Journal of Diagnostic Imaging 2 (2017), 31-34. doi:10.5455/jdi.20170608104413



MLA (The Modern Language Association) Style

Cubbison, Alyssa, Piotr Obara, and Terrence Demos. "Voriconazole-Induced Periostitis: A Radiographic Progression." Journal of Diagnostic Imaging 2.2 (2017), 31-34. Print. doi:10.5455/jdi.20170608104413



APA (American Psychological Association) Style

Cubbison, A., Obara, P. & Demos, T. (2017) Voriconazole-Induced Periostitis: A Radiographic Progression. Journal of Diagnostic Imaging , 2 (2), 31-34. doi:10.5455/jdi.20170608104413





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